On the surface, Friendly Fire has no advantages and is a hindrance (for example, teammates must get out of the way of projectiles). However, it does give rise to some new strategies:
- Teammates can be healed by using an energy projectile and PSI Magnet, or can use Oil Panic to capture friendly projectiles.
- Teammates can be used as ammunition when thrown or spit, and their Neutral Special Move can be copied by a friendly Kirby.
- Teammates can attack recovering friendlies to allow the re-use of an Up Special Move.
- Teammates can attack each other to replenish their attacks.
Official tournaments for all three games require that Friendly Fire be turned on. This forces extra co-ordination and tends to deter two-on-one combos.
In most one-player modes, friendly fire is turned off so enemies such as the Alloys cannot hit each other. This also applies to the player team in co-op Target Tests and the like.